MicroRNA 223 Targeting ATG16L1 Affects Microglial Autophagy in the Kainic Acid Model of Temporal Lobe Epilepsy

MicroRNA 223 Targeting ATG16L1 Affects Microglial Autophagy in the Kainic Acid Model of Temporal Lobe Epilepsy

This study aimed to explore whether microRNA (miR) 223 affects microglial autophagy by targeting autophagy-related 16-like 1 (ATG16L1) in the kainic acid (KA) model of temporal lobe epilepsy (TLE). The miRNA and mRNA expression levels were quantified using quantitative real-time polymerase chain rea...

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Bibliographic Details
Main Authors: Zhuoyi He, Houminji Chen, Yongsheng Zhong, Qihang Yang, Xuemin Wang, Rongqing Chen, Yanwu Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neurology
Subjects:
miR-223
microRNAs
epilepsy
hippocampus
microglia
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.704550/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.704550/full

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