Examining the feasibility of clinical grade CD271+ enrichment of mesenchymal stromal cells for bone regeneration.

<h4>Introduction</h4>Current clinical trials utilize mesenchymal stromal cells (MSCs) expanded in culture, however these interventions carry considerable costs and concerns pertaining to culture-induced losses of potency. This study assessed the feasibility of new clinical-grade technolo...

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Bibliographic Details
Main Authors: Richard J Cuthbert, Peter V Giannoudis, Xiao N Wang, Lindsay Nicholson, David Pawson, Anatole Lubenko, Hiang B Tan, Anne Dickinson, Dennis McGonagle, Elena Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0117855