Acute Synthesis of CPEB Is Required for Plasticity of Visual Avoidance Behavior in Xenopus

Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to plasticity-inducing stimuli remains unclear. We used in vivo bio-orthogonal noncanonical amino acid tagging (BONCAT) with the methionine analog azidohomoalanine (AHA) combined with t...

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Bibliographic Details
Main Authors: Wanhua Shen, Han-Hsuan Liu, Lucio Schiapparelli, Daniel McClatchy, Hai-yan He, John R. Yates III, Hollis T. Cline
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714000412