A Common Pituitary Autoantibody in Two Patients with Immune Checkpoint Inhibitor-Mediated Hypophysitis: ZCCHC8

ABSTRACT: Objective: Hypophysitis is an increasingly recognized adverse effect of immune checkpoint inhibitor (ICI) therapy for malignancy. However, the mechanisms through which ICIs induce hypophysitis are largely unknown. We aim to describe 2 cases of ICI-mediated hypophysitis and perform autoant...

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Bibliographic Details
Main Authors: Amanda Leiter, MD, MSCR, Sacha Gnjatic, PhD, Mary Fowkes, MD, PhD, Seunghee Kim-Schulze, PhD, Ilaria Laface, PhD, Matthew D. Galsky, MD, Emily J. Gallagher, MD, PhD
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:AACE Clinical Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520300079