Analysis of common <it>PTPN1 </it>gene variants in type 2 diabetes, obesity and associated phenotypes in the French population

<p>Abstract</p> <p>Background</p> <p>The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and energy homeostasis. PTP1B is encoded by the <it>PTPN1 </it>gene located on chromosome 20q13 sh...

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Bibliographic Details
Main Authors: Marre Michel, Balkau Beverley, Charpentier Guillaume, Bibi Amina, Dechaume Aurélie, Lecoeur Cécile, Cheyssac Claire, Froguel Philippe, Gibson Fernando, Vaxillaire Martine
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/7/44