Oxidação de proteínas por oxigênio singlete: mecanismos de dano, estratégias para detecção e implicações biológicas Singlet oxygen-mediated protein oxidation: damage mechanisms, detection techniques and biological implication

<abstract language="eng">Proteins are potential targets for singlet molecular oxygen (¹O2) oxidation. Damages occur only at tryptophan, tyrosine, histidine, methionine, and cysteine residues at physiological pH, generating oxidized compounds such as hydroperoxides. Therefore, it is i...

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Bibliographic Details
Main Authors: Graziella E. Ronsein, Sayuri Miyamoto, Etelvino Bechara, Paolo Di Mascio, Glaucia R. Martinez
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2006-06-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000300027