Progesterone receptor membrane component 1 and its role in ovarian follicle growth

Progesterone (P4) is synthesized in the ovary and acts directly on granulosa cells of developing ovarian follicles to suppress their rate of mitosis and apoptosis. Granulosa cells do not express nuclear progesterone receptor (PGR) but rather progesterone receptor membrane component-1 (PGRMC1). PGRMC...

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Bibliographic Details
Main Author: John J Peluso
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00099/full