Environmental Stressors and the Unfolded Protein Response (UPR) in Exocrine Pancreatic Function

The exocrine pancreas has the greatest synthetic capacity of any mammalian organ and as such is challenged with synthesis, processing and transporting a large load of digestive enzymes. Here we discuss how both mutations in the digestive enzymes and environmental factors impacting the pancreas such...

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Bibliographic Details
Main Authors: Stephen J Pandol, Fred eGorelick, Aurelia eLugea
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-03-01
Series:Frontiers in Physiology
Subjects:
upr
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00008/full