Detecting GPC3-Expressing Hepatocellular Carcinoma with L5 Peptide-Guided Pretargeting Approach: In Vitro and In Vivo MR Imaging Experiments

Detecting GPC3-Expressing Hepatocellular Carcinoma with L5 Peptide-Guided Pretargeting Approach: In Vitro and In Vivo MR Imaging Experiments

Objective. To investigate the potential of L5 peptide-guided pretargeting approach to identify GPC3-expressing hepatocellular carcinoma (HCC) using ultrasmall superparamagnetic iron oxide (USPIO) as the MR probe. Methods. Immunofluorescence with carboxyfluorescein- (FAM-) labeled L5 peptide was perf...

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Bibliographic Details
Main Authors: Weiyue Li, Xiang Xiao, Xiaodan Li, Yikai Xu, Lichao Ma, Liuji Guo, Chenggong Yan, Yuankui Wu
Format: Article
Language:English
Published: Hindawi-Wiley 2018-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2018/9169072

Internet

http://dx.doi.org/10.1155/2018/9169072

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