Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain.

Chronic renal fibrosis is the final common pathway of end stage renal disease caused by glomerular or tubular pathologies. Genetic background has a strong influence on the progression of chronic renal fibrosis. We recently found that Rowett black hooded rats were resistant to renal fibrosis. We aime...

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Bibliographic Details
Main Authors: Csaba Imre Szalay, Katalin Erdélyi, Gábor Kökény, Enikő Lajtár, Mária Godó, Csaba Révész, Tamás Kaucsár, Norbert Kiss, Márta Sárközy, Tamás Csont, Tibor Krenács, Gábor Szénási, Pál Pacher, Péter Hamar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0127090