Protein Conformational Changes in Breast Cancer Sera Using Infrared Spectroscopic Analysis

Protein Conformational Changes in Breast Cancer Sera Using Infrared Spectroscopic Analysis

Protein structural alterations, including misfolding and aggregation, are a hallmark of several diseases, including cancer. However, the possible clinical application of protein conformational analysis using infrared spectroscopy to detect cancer-associated structural changes in proteins has not bee...

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Bibliographic Details
Main Authors: Hemendra Ghimire, Chakravarthy Garlapati, Emiel A. M. Janssen, Uma Krishnamurti, Gengsheng Qin, Ritu Aneja, A. G. Unil Perera
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
ATR-FTIR
infrared spectroscopy
spectral deconvolution
serum
protein secondary structure
breast cancer biomarkers
Online Access:https://www.mdpi.com/2072-6694/12/7/1708

Internet

https://www.mdpi.com/2072-6694/12/7/1708

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