CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat

Neuroplastic changes in the dorsal striatum participate in the transition from casual to habitual drug use and might play a critical role in the development of methamphetamine (METH) addiction. We examined the influence of METH self-administration on gene and protein expression that may form substra...

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Bibliographic Details
Main Authors: Irina N. Krasnova, Margarit Chiflikyan, Zuzana Justinova, Michael T. McCoy, Bruce Ladenheim, Subramaniam Jayanthi, Cynthia Quintero, Christie Brannock, Chanel Barnes, Jordan E. Adair, Elin Lehrmann, Firas H. Kobeissy, Mark S. Gold, Kevin G. Becker, Steven R. Goldberg, Jean Lud Cadet
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Neurobiology of Disease
Subjects:
Methamphetamine
Self-administration
Dorsal striatum
ΔFosB
BDNF
pCREB
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113001514

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http://www.sciencedirect.com/science/article/pii/S0969996113001514

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