Radical-Mediated Reactions of α-Bromo Aluminium Thioacetals, α-Bromothioesters, and Xanthates for Thiolactone Synthesis

Radical-Mediated Reactions of α-Bromo Aluminium Thioacetals, α-Bromothioesters, and Xanthates for Thiolactone Synthesis

Thiolactones have attracted considerable attention in recent years as bioactive natural products, lead compounds for drug discovery, molecular probes, and reagents for polymerisation. We have investigated radical-mediated C-C bond forming reactions as a strategy for thiolactone synthesis. Cyclisatio...

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Bibliographic Details
Main Authors: Ruairí O. McCourt, Fabrice Dénès, Eoin M. Scanlan
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
radical fragmentation
radical cyclisation
thiyl radical
Online Access:http://www.mdpi.com/1420-3049/23/4/897

Internet

http://www.mdpi.com/1420-3049/23/4/897

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