CD209 genetic polymorphism and tuberculosis disease.

Tuberculosis causes significant morbidity and mortality worldwide, especially in sub-Saharan Africa. DC-SIGN, encoded by CD209, is a receptor capable of binding and internalizing Mycobacterium tuberculosis. Previous studies have reported that the CD209 promoter single nucleotide polymorphism (SNP)-3...

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Main Authors: Fredrik O Vannberg, Stephen J Chapman, Chiea C Khor, Kerrie Tosh, Sian Floyd, Dolly Jackson-Sillah, Amelia Crampin, Lifted Sichali, Boubacar Bah, Per Gustafson, Peter Aaby, Keith P W J McAdam, Oumou Bah-Sow, Christian Lienhardt, Giorgio Sirugo, Paul Fine, Adrian V S Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2148105?pdf=render