Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease

Abstract Background There is no consensus about which hippocampal subfields become atrophic earliest in the course of Alzheimer's disease (AD). Methods Thirty AD patients, 41 mild cognitive impairment (MCI) patients, and 38 healthy controls (HCs) underwent cerebral magnetic resonance imaging (w...

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Bibliographic Details
Main Authors: Giovanni A. Carlesimo, Fabrizio Piras, Maria Donata Orfei, Mariangela Iorio, Carlo Caltagirone, Gianfranco Spalletta
Format: Article
Language:English
Published: Wiley 2015-03-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Online Access:https://doi.org/10.1016/j.dadm.2014.12.001