Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity

Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity

Amyotrophic lateral sclerosis (ALS) is a clinical subtype of motor neurone disease (MND), a fatal neurodegenerative disease involving the loss of both the upper and lower motor neurones from the motor cortex, brainstem, and spinal cord. Identifying specific disease biomarkers would help to not only...

Full description

Bibliographic Details
Main Authors: Rachel Waller, Matthew Wyles, Paul R. Heath, Mbombe Kazoka, Helen Wollff, Pamela J. Shaw, Janine Kirby
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
cerebrospinal fluid
small RNA sequencing
microRNAs
biomarker
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00731/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00731/full

Similar Items