Construction of uricase-overproducing strains of <it>Hansenula polymorpha </it>and its application as biological recognition element in microbial urate biosensor

<p>Abstract</p> <p>Background</p> <p>The detection and quantification of uric acid in human physiological fluids is of great importance in the diagnosis and therapy of patients suffering from a range of disorders associated with altered purine metabolism, most notably g...

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Bibliographic Details
Main Authors: Schuhmann Wolfgang, Dmytruk Olena V, Smutok Oleh V, Dmytruk Kostyantyn V, Sibirny Andriy A
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Biotechnology
Subjects:
Online Access:http://www.biomedcentral.com/1472-6750/11/58