Induction of Monocyte Chemoattractant Proteins in Macrophages via the Production of Granulocyte-macrophage Colony Stimulating Factor by Breast Cancer Cells

Induction of Monocyte Chemoattractant Proteins in Macrophages via the Production of Granulocyte-macrophage Colony Stimulating Factor by Breast Cancer Cells

Monocyte chemoattractant protein-1 (MCP-1)/CCL2 plays an important role in the initiation and progression of cancer. We previously reported that in 4T1 murine breast cancer, non-tumor stromal cells, including macrophages, were the major source of MCP-1. In the present study, we analyzed the potent...

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Bibliographic Details
Main Authors: Teizo eYoshimura, Tomozumi eImamichi, Jonathan M. Weiss, Miwa eSato, Liangzhu eLi, Akihiro eMatsukawa, Ji Ming eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
Chemokines
Inflammation
Tumor Microenvironment
breast cancer
monocytes/macrophages
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00002/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00002/full

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