An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques.

BACKGROUND:New interventions for tuberculosis are urgently needed. Non-human primate (NHP) models provide the most relevant pre-clinical models of human disease and play a critical role in vaccine development. Models utilising Asian cynomolgus macaque populations are well established but the restric...

Full description

Bibliographic Details
Main Authors: S A Sharpe, A D White, L Sibley, F Gleeson, G A Hall, R J Basaraba, A McIntyre, S O Clark, K Gooch, P D Marsh, A Williams, M J Dennis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5342172?pdf=render