Sequence of a complete chicken BG haplotype shows dynamic expansion and contraction of two gene lineages with particular expression patterns.

Many genes important in immunity are found as multigene families. The butyrophilin genes are members of the B7 family, playing diverse roles in co-regulation and perhaps in antigen presentation. In humans, a fixed number of butyrophilin genes are found in and around the major histocompatibility comp...

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Main Authors: Jan Salomonsen, John A Chattaway, Andrew C Y Chan, Aimée Parker, Samuel Huguet, Denise A Marston, Sally L Rogers, Zhiguang Wu, Adrian L Smith, Karen Staines, Colin Butter, Patricia Riegert, Olli Vainio, Line Nielsen, Bernd Kaspers, Darren K Griffin, Fengtang Yang, Rima Zoorob, Francois Guillemot, Charles Auffray, Stephan Beck, Karsten Skjødt, Jim Kaufman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4046983?pdf=render