Distinct vascular genomic response of proton and gamma radiation-A pilot investigation.

The cardiovascular biology of proton radiotherapy is not well understood. We aimed to compare the genomic dose-response to proton and gamma radiation of the mouse aorta to assess whether their vascular effects may diverge. We performed comparative RNA sequencing of the aorta following (4 hrs) total-...

Full description

Bibliographic Details
Main Authors: Emanuela Ricciotti, Dimitra Sarantopoulou, Gregory R Grant, Jenine K Sanzari, Gabriel S Krigsfeld, Amber J Kiliti, Ann R Kennedy, Tilo Grosser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0207503