From single molecule fluctuations to muscle contraction: a Brownian model of A.F. Huxley's hypotheses.

Muscular force generation in response to external stimuli is the result of thermally fluctuating, cyclical interactions between myosin and actin, which together form the actomyosin complex. Normally, these fluctuations are modelled using transition rate functions that are based on muscle fiber behav...

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Bibliographic Details
Main Authors: Lorenzo Marcucci, Toshio Yanagida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3397984?pdf=render