Persistent Increased Frequency of Genomic Instability in Women Diagnosed with Breast Cancer: Before, during, and after Treatments

This study aimed to evaluate DNA damage in patients with breast cancer before treatment (background) and after chemotherapy (QT) and radiotherapy (RT) treatment using the Comet assay in peripheral blood and the micronucleus test in buccal cells. We also evaluated repair of DNA damage after the end o...

Full description

Bibliographic Details
Main Authors: Márcia Fernanda Correia Jardim Paz, André Luiz Pinho Sobral, Jaqueline Nascimento Picada, Ivana Grivicich, Antonio Luiz Gomes Júnior, Ana Maria Oliveira Ferreira da Mata, Marcus Vinícius Oliveira Barros de Alencar, Rodrigo Mendes de Carvalho, Kátia da Conceição Machado, Muhammad Torequl Islam, Ana Amélia de Carvalho Melo Cavalcante, Juliana da Silva
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2846819