Amphetamine elicits opposing actions on readily releasable and reserve pools for dopamine.

Amphetamine, a highly addictive drug with therapeutic efficacy, exerts paradoxical effects on the fundamental communication modes employed by dopamine neurons in modulating behavior. While amphetamine elevates tonic dopamine signaling by depleting vesicular stores and driving non-exocytotic release...

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Bibliographic Details
Main Authors: Dan P Covey, Steven A Juliano, Paul A Garris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3643976?pdf=render