c-MET as a potential therapeutic target and biomarker in cancer
The receptor tyrosine kinase c-MET and its ligand, hepatocyte growth factor (HGF), regulate multiple cellular processes that stimulate cell proliferation, invasion and angiogenesis. This review provides an overview of the evidence to support c-MET or the HGF/c-MET signaling pathway as relevant targe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-11-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/1758834011422557 |