c-MET as a potential therapeutic target and biomarker in cancer

The receptor tyrosine kinase c-MET and its ligand, hepatocyte growth factor (HGF), regulate multiple cellular processes that stimulate cell proliferation, invasion and angiogenesis. This review provides an overview of the evidence to support c-MET or the HGF/c-MET signaling pathway as relevant targe...

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Bibliographic Details
Main Authors: J. Rafael Sierra, Ming-Sound Tsao
Format: Article
Language:English
Published: SAGE Publishing 2011-11-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834011422557