Inhibition of HIV-1 infection by TNPO3 depletion is determined by capsid and detectable after viral cDNA enters the nucleus

<p>Abstract</p> <p>Background</p> <p>HIV-1 infects non-dividing cells. This implies that the virus traverses the nuclear pore before it integrates into chromosomal DNA. Recent studies demonstrated that TNPO3 is required for full infectivity of HIV-1. The fact that TNPO3...

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Bibliographic Details
Main Authors: De Iaco Alberto, Luban Jeremy
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Retrovirology
Subjects:
Online Access:http://www.retrovirology.com/content/8/1/98