Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age‐Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury

Early Intravenous Infusion of Mesenchymal Stromal Cells Exerts a Tissue Source Age‐Dependent Beneficial Effect on Neurovascular Integrity and Neurobehavioral Recovery After Traumatic Cervical Spinal Cord Injury

Abstract Localized vascular disruption after traumatic spinal cord injury (SCI) triggers a cascade of secondary events, including inflammation, gliosis, and scarring, that can further impact recovery. In addition to immunomodulatory and neurotrophic properties, mesenchymal stromal cells (MSCs) posse...

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Bibliographic Details
Main Authors: Reaz Vawda, Anna Badner, James Hong, Mirriam Mikhail, Alam Lakhani, Rachel Dragas, Kristiana Xhima, Tanya Barretto, Clifford L. Librach, Michael G. Fehlings
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:Stem Cells Translational Medicine
Subjects:
Mesenchymal stromal cells
Cervical spinal cord injury
Vascular disruption
Online Access:https://doi.org/10.1002/sctm.18-0192

Internet

https://doi.org/10.1002/sctm.18-0192

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