PET imaging of CXCR4 using copper-64 labeled peptide antagonist

<p>Expression of CXCR4 in cancer has been found to correlate with poor prognosis and resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide antagonist, T140-2D, that can be labeled easily with the PET isotope copper-64, and thereby enable <i>in vivo</...

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Bibliographic Details
Main Author: Orit Jacobson, Ido D. Weiss, Lawrence P. Szajek, Gang Niu, Ying Ma, Dale O. Kiesewetter, Joshua M. Farber, Xiaoyuan Chen
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Theranostics
Online Access:http://www.thno.org/v01p0251.htm