A Unique Case of Bilateral Thalamic High-Grade Glioma in a Pediatric Patient with LI-Fraumeni Syndrome: Case Presentation and Review of the Literature

A Unique Case of Bilateral Thalamic High-Grade Glioma in a Pediatric Patient with LI-Fraumeni Syndrome: Case Presentation and Review of the Literature

Li-Fraumeni syndrome (LFS) is a rare high-penetrance and autosomal-dominant pathological condition caused by the germline mutation of the TP53 gene, predisposing to the development of tumors from pediatric age. We conducted a qualitative systematic review following the ENTREQ (Enhancing Transparency...

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Bibliographic Details
Main Authors: Raffaella Messina, Gerardo Cazzato, Teresa Perillo, Vita Stagno, Valeria Blè, Mariachiara Resta, Francesco De Leonardis, Nicola Santoro, Francesco Signorelli, Giuseppe Ingravallo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Neurology International
Subjects:
Li-Fraumeni syndrome
embryonal rhabdomyosarcoma
high-grade bithalamic glioma
NTRK genes
p53 protein
Online Access:https://www.mdpi.com/2035-8377/13/2/17

Internet

https://www.mdpi.com/2035-8377/13/2/17

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