Regioselective Synthesis of New 2,4-(Het)aryl-3<i>H</i>-pyrido[1′,2′:1,5]pyrazolo[4,3-<i>d</i>]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions

Regioselective Synthesis of New 2,4-(Het)aryl-3<i>H</i>-pyrido[1′,2′:1,5]pyrazolo[4,3-<i>d</i>]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions

The design of some novel di-(het)arylated-3<i>H</i>-pyrido[1&#8242;,2&#8242;:1,5]pyrazolo[4,3-<i>d</i>]pyrimidine derivatives is reported. The series was developed from 1-aminopyridinium iodide, which afforded the key intermediate bearing two thiomethyl and amide func...

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Bibliographic Details
Main Authors: Abdelaziz Ejjoummany, Rabia Belaroussi, Ahmed El Hakmaoui, Mohamed Akssira, Gérald Guillaumet, Frédéric Buron, Sylvain Routier
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
pyridopyrazolopyrimidine
pyBroP activation
palladium cross-coupling
Online Access:https://www.mdpi.com/1420-3049/23/11/2740

Internet

https://www.mdpi.com/1420-3049/23/11/2740

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