TP53/MicroRNA Interplay in Hepatocellular Carcinoma

The role of microRNAs as oncogenes and tumor suppressor genes has emerged in several cancers, including hepatocellular carcinoma (HCC). The pivotal tumor suppressive role of p53-axis is indicated by the presence of inactivating mutations in TP53 gene in nearly all cancers. A close interaction betwee...

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Bibliographic Details
Main Authors: Daniela Pollutri, Laura Gramantieri, Luigi Bolondi, Francesca Fornari
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
p53
Online Access:http://www.mdpi.com/1422-0067/17/12/2029