Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

Abstract Background Toxocara canis is quite closely related to Ascaris suum but its biology is more complex, involving a phase of arrested development (diapause or hypobiosis) in tissues as well as transplacental and transmammary transmission routes. In the present study, we explored and compared da...

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Bibliographic Details
Main Authors: Guangxu Ma, Tao Wang, Pasi K. Korhonen, Shuai Nie, Gavin E. Reid, Andreas J. Stroehlein, Anson V. Koehler, Bill C. H. Chang, Andreas Hofmann, Neil D. Young, Robin B. Gasser
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Parasites & Vectors
Subjects:
Toxocara canis
Ascaris suum
Dauer signalling pathway
Dafachronic acid
Arrested development
Online Access:http://link.springer.com/article/10.1186/s13071-018-3265-y

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http://link.springer.com/article/10.1186/s13071-018-3265-y

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