Studying pre-treatment and ketamine-induced changes in white matter microstructure in the context of ketamine’s antidepressant effects

Abstract Ketamine is increasingly being used as a therapeutic for treatment-resistant depression (TRD), yet the effects of ketamine on the human brain remain largely unknown. This pilot study employed diffusion magnetic resonance imaging (dMRI) to examine relationships between ketamine treatment and...

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Bibliographic Details
Main Authors: Valerie J. Sydnor, Amanda E. Lyall, Suheyla Cetin-Karayumak, Joey C. Cheung, Julia M. Felicione, Oluwaseun Akeju, Martha E. Shenton, Thilo Deckersbach, Dawn F. Ionescu, Ofer Pasternak, Cristina Cusin, Marek Kubicki
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-020-01122-8