Tyrosine Kinase Inhibitors in Pulmonary Vascular Disease

Tyrosine Kinase Inhibitors in Pulmonary Vascular Disease

Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder, characterized by proliferation of granulocytes, caused by a translocation that produces the Philadelphia chromosome resulting in constitutively active BCR-ABL tyrosine kinase. Imatinib and dasatinib are 2 BCR-ABL tyrosine kinase...

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Bibliographic Details
Main Author: John J. Ryan, MD
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:JACC: Basic to Translational Science
Subjects:
chronic myeloid leukemia
pulmonary arterial hypertension
pulmonary hypertension
right heart failure
tyrosine kinase inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X16301711

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http://www.sciencedirect.com/science/article/pii/S2452302X16301711

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