Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.

Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.

BACKGROUND:The existence of cancer stem cells (CSCs) or cancer stem-like cells in a tumor mass is believed to be responsible for tumor recurrence because of their intrinsic and extrinsic drug-resistance characteristics. Therefore, targeted killing of CSCs would be a newer strategy for the prevention...

Full description

Bibliographic Details
Main Authors: Bin Bao, Shadan Ali, Dejuan Kong, Sanila H Sarkar, Zhiwei Wang, Sanjeev Banerjee, Amro Aboukameel, Subhash Padhye, Philip A Philip, Fazlul H Sarkar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3052388?pdf=render

Internet

http://europepmc.org/articles/PMC3052388?pdf=render

Similar Items