miR-27a-5p—Abundant Small Extracellular Vesicles Derived From Epimedium-Preconditioned Bone Mesenchymal Stem Cells Stimulate Osteogenesis by Targeting Atg4B-Mediated Autophagy

miR-27a-5p—Abundant Small Extracellular Vesicles Derived From Epimedium-Preconditioned Bone Mesenchymal Stem Cells Stimulate Osteogenesis by Targeting Atg4B-Mediated Autophagy

Osteoporosis (OP) is a disease affecting the elderly and is characterized by incremental fractures and bone fragility. Small extracellular vesicles (sEVs) derived from mesenchymal stem cells have been demonstrated to possess potent regeneration potential. In this study, we evaluated the osteogenesis...

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Bibliographic Details
Main Authors: Xiaoyun Li, Rumeng Chen, Yunchuan Li, Panpan Wang, Yan Cui, Li Yang, Xiaofeng Zhu, Ronghua Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
small extracellular vesicle
miR-27a-5p
bone mesenchymal stem cell
osteogenesis
Epimedium
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.642646/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.642646/full

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