Characterizing complex polysera produced by antigen-specific immunization through the use of affinity-selected mimotopes.

BACKGROUND: Antigen-based (as opposed to whole organism) vaccines are actively being pursued for numerous indications. Even though different formulations may produce similar levels of total antigen-specific antibody, the composition of the antibody response can be quite distinct resulting in differe...

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Bibliographic Details
Main Authors: Galina Denisova, Dimitri Denisov, Carole Evelegh, Michaela Weissgram, Jochen Beck, Stephen Ronan Foley, Jonathan Lorne Bramson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2668798?pdf=render