Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization

Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization

Abstract Background Squamous cell carcinoma is the dominant type of esophageal cancer in China with many patients initially diagnosed at advanced stage. Patient-derived xenografts (PDX) models have been developed to be an important platform for preclinical research. This study aims to establish and...

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Bibliographic Details
Main Authors: Jianling Zou, Ying Liu, Jingyuan Wang, Zhentao Liu, Zhihao Lu, Zuhua Chen, Zhongwu Li, Bin Dong, Wenwen Huang, Yanyan Li, Jing Gao, Lin Shen
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Translational Medicine
Subjects:
Patient-derived xenograft model
Esophageal squamous cell carcinoma
Biopsy
Genomic characterizations
Online Access:http://link.springer.com/article/10.1186/s12967-018-1379-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1379-9

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