Continentalic Acid Rather Than Kaurenoic Acid Is Responsible for the Anti-Arthritic Activity of Manchurian Spikenard In Vitro and In Vivo

The aim of this study was to identify the active compound responsible for the pharmacological activities of Manchurian spikenard (<i>Aralia continentalis</i> Kitag.). Interleukin (IL)-1&#946;-stimulated human chondrocytes and monoiodoacetate (MIA)-induced osteoarthritic rats were tre...

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Bibliographic Details
Main Authors: Riwon Hong, Kyoung Soo Kim, Gwang Muk Choi, Mijung Yeom, Bombi Lee, Sanghyun Lee, Ki Sung Kang, Hyang Sook Lee, Hi-Joon Park, Dae-Hyun Hahm
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/21/5488