Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma

Basal cell carcinoma (BCC) is the most common neoplasm in the Caucasian population. Only a fraction of BCC exhibits pigmentation. Lack of melanocyte colonization has been suggested to be due to p53-inactivating mutations in the BCC cells interfering with the p53-proopiomelanocortin pathway and the p...

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Bibliographic Details
Main Authors: Lídia M. Frey, Roland Houben, Eva-B. Bröcker
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2011/349726