Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the most common neoplasm in the Caucasian population. Only a fraction of BCC exhibits pigmentation. Lack of melanocyte colonization has been suggested to be due to p53-inactivating mutations in the BCC cells interfering with the p53-proopiomelanocortin pathway and the p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
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Series: | Journal of Skin Cancer |
Online Access: | http://dx.doi.org/10.1155/2011/349726 |