Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants

Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants

Acute promyelocytic leukemia (APL) is a special disease entity of acute myeloid leukemia (AML). The clinical use of all-trans retinoic acid (ATRA) has transformed APL into the most curable form of AML. The majority of APL cases are characterized by the fusion gene PML-RARA. Although the PML-RARA fus...

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Bibliographic Details
Main Authors: Abdul Mannan, Ibrahim N. Muhsen, Eva Barragán, Miguel A. Sanz, Mohamad Mohty, Shahrukh K. Hashmi, Mahmoud Aljurf
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
Acute promyelocytic leukemia
Chimeric proteins
Fusion genes
RARA
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387620301059

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http://www.sciencedirect.com/science/article/pii/S1658387620301059

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