Cathelicidin Insufficiency in Patients with Fatal Leptospirosis.

Cathelicidin Insufficiency in Patients with Fatal Leptospirosis.

Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10-50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms...

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Bibliographic Details
Main Authors: Janet C Lindow, Elsio A Wunder, Stephen J Popper, Jin-Na Min, Praveen Mannam, Anup Srivastava, Yi Yao, Kathryn P Hacker, Khadir Raddassi, Patty J Lee, Ruth R Montgomery, Albert C Shaw, Jose E Hagan, Guilherme C Araújo, Nivison Nery, David A Relman, Charles C Kim, Mitermayer G Reis, Albert I Ko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005943

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https://doi.org/10.1371/journal.ppat.1005943

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