Metformin protects skeletal muscle from cardiotoxin induced degeneration.

The skeletal muscle tissue has a remarkable capacity to regenerate upon injury. Recent studies have suggested that this regenerative process is improved when AMPK is activated. In the muscle of young and old mice a low calorie diet, which activates AMPK, markedly enhances muscle regeneration. Remark...

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Bibliographic Details
Main Authors: Francesca Langone, Stefano Cannata, Claudia Fuoco, Daniele Lettieri Barbato, Stefano Testa, Aurelio Pio Nardozza, Maria Rosa Ciriolo, Luisa Castagnoli, Cesare Gargioli, Gianni Cesareni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4252070?pdf=render