Metformin protects skeletal muscle from cardiotoxin induced degeneration.
The skeletal muscle tissue has a remarkable capacity to regenerate upon injury. Recent studies have suggested that this regenerative process is improved when AMPK is activated. In the muscle of young and old mice a low calorie diet, which activates AMPK, markedly enhances muscle regeneration. Remark...
Main Authors: | Francesca Langone, Stefano Cannata, Claudia Fuoco, Daniele Lettieri Barbato, Stefano Testa, Aurelio Pio Nardozza, Maria Rosa Ciriolo, Luisa Castagnoli, Cesare Gargioli, Gianni Cesareni |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4252070?pdf=render |
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