The Mechanism of Asparagine Endopeptidase in the Progression of Malignant Tumors: A Review

Asparagine endopeptidase (AEP), also called legumain, is currently the only known cysteine protease that specifically cleaves peptide bonds in asparaginyl residue in the mammalian genome. Since 2003, AEP has been reported to be widely expressed in a variety of carcinomas and is considered a potentia...

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Bibliographic Details
Main Authors: Wenrui Zhang, Yingying Lin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/5/1153