MMP-9 inhibitors impair learning in spontaneously hypertensive rats.

MMP-9 inhibitors impair learning in spontaneously hypertensive rats.

Vascular cognitive impairment dementia (VCID) is a major cause of cognitive loss in the elderly. Matrix metalloproteinases (MMPs) are a family of proteases involved in remodeling the extracellular matrix in development, injury and repair. Blood-brain barrier (BBB) disruption due to inflammation medi...

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Bibliographic Details
Main Authors: Limor Raz, Yi Yang, Jeffrey Thompson, Sasha Hobson, John Pesko, Shahriar Mobashery, Mayland Chang, Gary Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208357

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https://doi.org/10.1371/journal.pone.0208357

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