Vaccination with Combination DNA and Virus-Like Particles Enhances Humoral and Cellular Immune Responses upon Boost with Recombinant Modified Vaccinia Virus Ankara Expressing Human Immunodeficiency Virus Envelope Proteins

Vaccination with Combination DNA and Virus-Like Particles Enhances Humoral and Cellular Immune Responses upon Boost with Recombinant Modified Vaccinia Virus Ankara Expressing Human Immunodeficiency Virus Envelope Proteins

Heterologous prime boost with DNA and recombinant modified vaccinia virus Ankara (rMVA) vaccines is considered as a promising vaccination approach against human immunodeficiency virus (HIV-1). To further enhance the efficacy of DNA-rMVA vaccination, we investigated humoral and cellular immune respon...

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Bibliographic Details
Main Authors: Sailaja Gangadhara, Young-Man Kwon, Subbiah Jeeva, Fu-Shi Quan, Baozhong Wang, Bernard Moss, Richard W. Compans, Rama Rao Amara, M. Abdul Jabbar, Sang-Moo Kang
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Vaccines
Subjects:
HIV vaccines
DNA
VLPs
recombinant MVA
Online Access:https://www.mdpi.com/2076-393X/5/4/52

Internet

https://www.mdpi.com/2076-393X/5/4/52

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