Pilot scale production of highly efficacious and stable enterovirus 71 vaccine candidates.

BACKGROUND: Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia and now is being recognized as an important neurotropic virus. Effective medications and prophylactic vaccine against EV71 infection are urgently needed. Based on the success of inactivated...

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Main Authors: Ai-Hsiang Chou, Chia-Chyi Liu, Cheng-Peng Chang, Meng-Shin Guo, Shih-Yang Hsieh, Wen-Hsueh Yang, Hsin-Ju Chao, Chien-Long Wu, Ju-Lan Huang, Min-Shi Lee, Alan Yung-Chi Hu, Sue-Chen Lin, Yu-Yun Huang, Mei-Hua Hu, Yen-Hung Chow, Jen-Ron Chiang, Jui-Yuan Chang, Pele Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3328501?pdf=render