MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12

MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12

Abstract Background Cancer stem cells (CSCs) play an important role in the development of pancreatic cancer. We previously showed that the microRNA miR-137 is downregulated in clinical samples of pancreatic cancer, and its expression negatively regulates the proliferation and invasiveness of pancrea...

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Bibliographic Details
Main Authors: Zhiwei He, Xingjun Guo, She Tian, Changhao Zhu, Shiyu Chen, Chao Yu, Jianxin Jiang, Chengyi Sun
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-137
Pancreatic cancer
KLF12
Stemness
Online Access:http://link.springer.com/article/10.1186/s13046-019-1105-3

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http://link.springer.com/article/10.1186/s13046-019-1105-3

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