Extracellular ATP hydrolysis inhibits synaptic transmission by increasing ph buffering in the synaptic cleft.

Neuronal computations strongly depend on inhibitory interactions. One such example occurs at the first retinal synapse, where horizontal cells inhibit photoreceptors. This interaction generates the center/surround organization of bipolar cell receptive fields and is crucial for contrast enhancement....

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Bibliographic Details
Main Authors: Rozan Vroman, Lauw J Klaassen, Marcus H C Howlett, Valentina Cenedese, Jan Klooster, Trijntje Sjoerdsma, Maarten Kamermans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4028192?pdf=render